The daughter of an 85-year-old woman with mild Alzheimer disease says her mother has become "a different person" over the past 2 days. Which finding most strongly suggests superimposed delirium rather than progression of dementia?
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Answer: A
Sudden inattention that fluctuates over the course of the day: Correct. Delirium starts suddenly, its course fluctuates and inattention is a core feature, matching CAM criteria. It needs a search for causes such as infection, drugs or dehydration.
Slowly worsening short-term memory over the past 2 years: Gradual memory decline over years is typical of Alzheimer disease progression, not delirium.
Persistent sadness and poor appetite for the past 6 weeks: Weeks of low mood with appetite change suggest depression, which develops more slowly and without fluctuating attention.
Trouble finding words that has been stable over many months: Stable language deficits are part of the dementia picture, not an acute change.
Delirium = sudden onset, fluctuating course, inattention, plus disorganized thinking or altered alertness (CAM). It is a medical emergency, even in a person with dementia.