PANRE Practice Test 2026 — Free PANRE Exam Prep Questions
The PANRE and its longitudinal version, PANRE-LA, are the NCCPA recertification assessments that Board Certified PAs take in the last years of each 10-year certification cycle. Both test the core medical knowledge every PA needs, whatever their specialty. Our original clinical vignettes follow the PANRE/PANRE-LA content blueprint by organ system and performance expectation, with an explanation for every option.
A 68-year-old man has bothersome urinary hesitancy, a weak stream and nocturia. His prostate is smooth, symmetric and mildly enlarged (estimated 30 g), urinalysis is normal and post-void residual is low. He wants the medication that gives the fastest symptom relief. Which is most appropriate?
PANRE format, scoring & key facts
PANRE at Pearson VUE test centers; PANRE-LA online on your own device each quarter.
Facts last verified Oct 5, 2026. Source: www.nccpa.net/wp-content/uploads/PANRE-PANRELA-CB.pdf. Always confirm details with NCCPA before your exam.
When can you take the PANRE?
Plan backwards from your exam date
What the PANRE covers
Every PrepBanq PANRE test mirrors the official domain weights.
Domain distribution
% of the exam| Content domain | Weight | ≈ Questions on exam | Our practice questions |
|---|---|---|---|
Cardiovascular SystemCoronary disease, arrhythmias, heart failure, hypertension, vascular disease and valvular disorders. | 12% | ~29 | 3 questions → |
Pulmonary SystemAsthma, COPD, pneumonia, pleural disease, pulmonary embolism, croup and sleep apnea. | 10% | ~24 | 3 questions → |
Gastrointestinal System and/or NutritionHepatobiliary and pancreatic disease, GI bleeding, inflammatory and functional bowel disease, food intolerances. | 10% | ~24 | 2 questions → |
Endocrine SystemDiabetes and its emergencies, thyroid, parathyroid and adrenal disease, osteoporosis and metabolic syndrome. | 8% | ~19 | 2 questions → |
Eyes, Ears, Nose, and ThroatOcular emergencies, otitis, sinusitis, pharyngitis and deep neck infections, hearing loss and vertigo. | 8% | ~19 | 2 questions → |
Musculoskeletal SystemFractures, crystal and inflammatory arthropathies, compartment syndrome, spinal disorders and sports injuries. | 8% | ~19 | 2 questions → |
Infectious Diseases and Hematologic SystemInfectious Diseases (7%): sepsis, tick-borne, viral and sexually transmitted infections. Hematologic System (4%): anemias, coagulopathies and hematologic cancers. | 11% | ~26 | 3 questions → |
Neurologic System and Psychiatry/Behavioral ScienceNeurologic System (5%): stroke, seizure, headache, neuropathy. Psychiatry/Behavioral Science (7%): mood, anxiety, substance use disorders and suicide risk. | 12% | ~29 | 3 questions → |
Genitourinary, Renal, and Reproductive SystemsGenitourinary (5%), Renal (4%: AKI, CKD, electrolytes) and Reproductive (5%: pregnancy, PID, gynecologic cancers). | 14% | ~34 | 3 questions → |
Dermatologic System and Emergent TopicsDermatologic System (5%): skin cancers, infections, eruptions. Emergent Topics (Legal, Ethical, DEI) (2%). | 7% | ~17 | 2 questions → |
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PANRE FAQ
How many questions are on the PANRE?
The PANRE has 240 questions and you have 4 hours to finish. Question types: Multiple choice. PANRE: 4 blocks of 60 questions, 60 minutes per block. PANRE-LA: 25 questions per quarter, 5 minutes per question, references allowed.
How long is the PANRE exam?
Testing time for the PANRE is 4 hours.
What is on the PANRE?
The PANRE covers Cardiovascular System (about 12%), Pulmonary System (about 10%), Gastrointestinal System and/or Nutrition (about 10%), Endocrine System (about 8%), Eyes, Ears, Nose, and Throat (about 8%), Musculoskeletal System (about 8%), Infectious Diseases and Hematologic System (about 11%), Neurologic System and Psychiatry/Behavioral Science (about 12%), Genitourinary, Renal, and Reproductive Systems (about 14%), Dermatologic System and Emergent Topics (about 7%).
Who administers the PANRE?
The Physician Assistant National Recertifying Exam (PANRE / PANRE-LA) is administered by NCCPA. Delivery: PANRE at Pearson VUE test centers; PANRE-LA online on your own device each quarter.
Is there a free PANRE practice test?
Yes. PrepBanq has 3 free PANRE practice tests with 25 exam-style questions in the real PANRE formats, and every answer is explained. No credit card is needed.
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