A veterinarian orders a drug at 2 mg/kg IV for a 44-lb dog. The drug concentration is 10 mg/mL. How many milliliters should be drawn up?
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Answer: B
8.8 mL: This uses the weight in pounds (44 × 2 = 88 mg ÷ 10); the dose is per kilogram, so pounds must be converted first.
4 mL: Correct. 44 lb ÷ 2.2 = 20 kg; 20 kg × 2 mg/kg = 40 mg; 40 mg ÷ 10 mg/mL = 4 mL.
0.4 mL: This is a decimal-place error — one-tenth of the correct volume, which would underdose the patient.
2 mL: 2 mL contains only 20 mg, which is 1 mg/kg — half the ordered dose.
Volume (mL) = weight (kg) × dose (mg/kg) ÷ concentration (mg/mL). Convert lb to kg by dividing by 2.2.