A patient with type 2 diabetes arrives for an oncologic F-18 FDG PET/CT after fasting 6 hours. Point-of-care blood glucose is 285 mg/dL. What is the most appropriate action?
Show answer & explanation
Answer: D
Inject FDG now and extend the uptake time to 120 minutes instead: Incorrect. A longer uptake time does not overcome high glucose competing with FDG for transport.
Give the patient's insulin dose, then inject FDG right away: Incorrect. Insulin shortly before FDG pushes tracer into muscle and fat, degrading the images.
Inject FDG at twice the usual activity to make up for it: Incorrect. Raising activity adds dose but does not fix poor tumor-to-background contrast.
Consult the physician and reschedule once glucose is controlled: Correct. Glucose competes with FDG; most protocols reschedule or consult when glucose is above about 150–200 mg/dL.
High blood glucose lowers tumor FDG uptake; check glucose before injection and follow the protocol threshold (often 200 mg/dL).